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Combinations of Freeze-Dried Amorphous Vardenafil Hydrochloride with Saccharides as a Way to Enhance Dissolution Rate and Permeability

To improve physicochemical properties of vardenafil hydrochloride (VAR), its amorphous form and combinations with excipients—hydroxypropyl methylcellulose (HPMC) and β-cyclodextrin (β-CD)—were prepared. The impact of the modification on physicochemical properties was estimated by comparing amorphous...

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Detalles Bibliográficos
Autores principales:	Wiergowska, Gabriela, Ludowicz, Dominika, Wdowiak, Kamil, Miklaszewski, Andrzej, Lewandowska, Kornelia, Cielecka-Piontek, Judyta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151567/ https://www.ncbi.nlm.nih.gov/pubmed/34064796 http://dx.doi.org/10.3390/ph14050453

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