CLCA1 Regulates Airway Mucus Production and Ion Secretion Through TMEM16A

TMEM16A, a Ca(2+)-activated chloride channel (CaCC), and its regulator, CLCA1, are associated with inflammatory airway disease and goblet cell metaplasia. CLCA1 is a secreted protein with protease activity that was demonstrated to enhance membrane expression of TMEM16A. Expression of CLCA1 is partic...

Descripción completa

Detalles Bibliográficos
Autores principales: Centeio, Raquel, Ousingsawat, Jiraporn, Schreiber, Rainer, Kunzelmann, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151571/
https://www.ncbi.nlm.nih.gov/pubmed/34066250
http://dx.doi.org/10.3390/ijms22105133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151571/
https://www.ncbi.nlm.nih.gov/pubmed/34066250
http://dx.doi.org/10.3390/ijms22105133

Ejemplares similares