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CLCA1 Regulates Airway Mucus Production and Ion Secretion Through TMEM16A
TMEM16A, a Ca(2+)-activated chloride channel (CaCC), and its regulator, CLCA1, are associated with inflammatory airway disease and goblet cell metaplasia. CLCA1 is a secreted protein with protease activity that was demonstrated to enhance membrane expression of TMEM16A. Expression of CLCA1 is partic...
Autores principales: | Centeio, Raquel, Ousingsawat, Jiraporn, Schreiber, Rainer, Kunzelmann, Karl |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151571/ https://www.ncbi.nlm.nih.gov/pubmed/34066250 http://dx.doi.org/10.3390/ijms22105133 |
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