Intertumoral Genetic Heterogeneity Generates Distinct Tumor Microenvironments in a Novel Murine Synchronous Melanoma Model

SIMPLE SUMMARY: Metastatic melanoma patients may present with multiple, simultaneous metastases that are genetically different. This intertumoral heterogeneity can cause these tumors to respond differently to the same systemic therapy. Progression of any one tumor, even when others regress, eventual...

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Detalles Bibliográficos
Autores principales: Qin, Shuyang S., Han, Booyeon J., Williams, Alyssa, Jackson, Katherine M., Jewell, Rachel, Chacon, Alexander C., Lord, Edith M., Linehan, David C., Kim, Minsoo, Reuben, Alexandre, Gerber, Scott A., Prieto, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151632/
https://www.ncbi.nlm.nih.gov/pubmed/34064795
http://dx.doi.org/10.3390/cancers13102293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151632/
https://www.ncbi.nlm.nih.gov/pubmed/34064795
http://dx.doi.org/10.3390/cancers13102293

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