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Correcting for Naturally Occurring Mass Isotopologue Abundances in Stable-Isotope Tracing Experiments with PolyMID

Stable-isotope tracing is a method to measure intracellular metabolic pathway utilization by feeding a cellular system a stable-isotope-labeled tracer nutrient. The power of the method to resolve differential pathway utilization is derived from the enrichment of metabolites in heavy isotopes that ar...

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Detalles Bibliográficos
Autores principales: Jeong, Heesoo, Yu, Yan, Johansson, Henrik J., Schroeder, Frank C., Lehtiö, Janne, Vacanti, Nathaniel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151723/
https://www.ncbi.nlm.nih.gov/pubmed/34066041
http://dx.doi.org/10.3390/metabo11050310