Excessive Iron Induces Oxidative Stress Promoting Cellular Perturbations and Insulin Secretory Dysfunction in MIN6 Beta Cells

Exposure to high levels of glucose and iron are co-related to reactive oxygen species (ROS) generation and dysregulation of insulin synthesis and secretion, although the precise mechanisms are not well clarified. The focus of this study was to examine the consequences of exposure to high iron levels...

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Detalles Bibliográficos
Autores principales: Blesia, Voni, Patel, Vinood B., Al-Obaidi, Hisham, Renshaw, Derek, Zariwala, Mohammed Gulrez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151797/
https://www.ncbi.nlm.nih.gov/pubmed/34065122
http://dx.doi.org/10.3390/cells10051141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151797/
https://www.ncbi.nlm.nih.gov/pubmed/34065122
http://dx.doi.org/10.3390/cells10051141

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