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Diclofenac N-Derivatives as Therapeutic Agents with Anti-Inflammatory and Anti-Cancer Effect

A series of diclofenac N-derivatives (2, 4, 6, 8c, 9c, 10a-c) were synthesized in order to test their anti-cancer and anti-inflammatory effects. The anticarcinogen activity has been assayed against three cancer cell lines: HT29, human colon cancer cells; Hep-G2, human hepatic cells; and B16-F10, mur...

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Detalles Bibliográficos
Autores principales: Galisteo, Alberto, Jannus, Fatin, García-García, Amalia, Aheget, Houssam, Rojas, Sara, Lupiañez, José A., Rodríguez-Diéguez, Antonio, Reyes-Zurita, Fernando J., Quílez del Moral, José F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151993/
https://www.ncbi.nlm.nih.gov/pubmed/34064702
http://dx.doi.org/10.3390/ijms22105067