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Ultrasensitive tau biosensor cells detect no seeding in Alzheimer’s disease CSF
Tau protein forms self-replicating assemblies (seeds) that may underlie progression of pathology in Alzheimer’s disease (AD) and related tauopathies. Seeding in recombinant protein preparations and brain homogenates has been quantified with “biosensor” cell lines that express tau with a disease-asso...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152020/ https://www.ncbi.nlm.nih.gov/pubmed/34039426 http://dx.doi.org/10.1186/s40478-021-01185-8 |