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Ultrasensitive tau biosensor cells detect no seeding in Alzheimer’s disease CSF

Tau protein forms self-replicating assemblies (seeds) that may underlie progression of pathology in Alzheimer’s disease (AD) and related tauopathies. Seeding in recombinant protein preparations and brain homogenates has been quantified with “biosensor” cell lines that express tau with a disease-asso...

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Detalles Bibliográficos
Autores principales:	Hitt, Brian D., Vaquer-Alicea, Jaime, Manon, Victor A., Beaver, Joshua D., Kashmer, Omar M., Garcia, Jan N., Diamond, Marc I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152020/ https://www.ncbi.nlm.nih.gov/pubmed/34039426 http://dx.doi.org/10.1186/s40478-021-01185-8

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