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Beneficial and harmful effects of antidepressants versus placebo, ‘active placebo’, or no intervention for adults with major depressive disorder: a protocol for a systematic review of published and unpublished data with meta-analyses and trial sequential analyses

BACKGROUND: Major depressive disorder is one of the most common, burdensome, and costly psychiatric disorders worldwide. Antidepressants are frequently used to treat major depressive disorder. It has been shown repeatedly that antidepressants seem to reduce depressive symptoms with a statistically s...

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Detalles Bibliográficos
Autores principales: Juul, Sophie, Siddiqui, Faiza, Barbateskovic, Marija, Jørgensen, Caroline Kamp, Hengartner, Michael Pascal, Kirsch, Irving, Gluud, Christian, Jakobsen, Janus Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152051/
https://www.ncbi.nlm.nih.gov/pubmed/34034811
http://dx.doi.org/10.1186/s13643-021-01705-6