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A new KSRP-binding compound suppresses distant metastasis of colorectal cancer by targeting the oncogenic KITENIN complex

BACKGROUND: Distant metastasis is the major cause of death in patients with colorectal cancer (CRC). Previously, we identified KITENIN as a metastasis-enhancing gene and suggested that the oncogenic KITENIN complex is involved in metastatic dissemination of KITENIN-overexpressing CRC cells. Here, we...

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Detalles Bibliográficos
Autores principales: Bae, Jeong A, Bae, Woo Kyun, Kim, Sung Jin, Ko, Yoo-Seung, Kim, Keon Young, Park, So-Yeon, Yu, Young Hyun, Kim, Eun Ae, Chung, Ik Joo, Kim, Hangun, Ha, Hyung-Ho, Kim, Kyung Keun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152081/
https://www.ncbi.nlm.nih.gov/pubmed/34039363
http://dx.doi.org/10.1186/s12943-021-01368-w