Cargando…
A new KSRP-binding compound suppresses distant metastasis of colorectal cancer by targeting the oncogenic KITENIN complex
BACKGROUND: Distant metastasis is the major cause of death in patients with colorectal cancer (CRC). Previously, we identified KITENIN as a metastasis-enhancing gene and suggested that the oncogenic KITENIN complex is involved in metastatic dissemination of KITENIN-overexpressing CRC cells. Here, we...
Autores principales: | Bae, Jeong A, Bae, Woo Kyun, Kim, Sung Jin, Ko, Yoo-Seung, Kim, Keon Young, Park, So-Yeon, Yu, Young Hyun, Kim, Eun Ae, Chung, Ik Joo, Kim, Hangun, Ha, Hyung-Ho, Kim, Kyung Keun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152081/ https://www.ncbi.nlm.nih.gov/pubmed/34039363 http://dx.doi.org/10.1186/s12943-021-01368-w |
Ejemplares similares
-
A peptide interfering with the dimerization of oncogenic KITENIN protein and its stability suppresses colorectal tumour progression
por: Kim, Sung Jin, et al.
Publicado: (2022) -
Intravenous KITENIN shRNA Injection Suppresses Hepatic Metastasis and Recurrence of Colon Cancer in an Orthotopic Mouse Model
por: Hwang, Jun-Eul, et al.
Publicado: (2011) -
KITENIN promotes aerobic glycolysis through PKM2 induction by upregulating the c-Myc/hnRNPs axis in colorectal cancer
por: Varlı, Mücahit, et al.
Publicado: (2023) -
KITENIN promotes glioma invasiveness and progression, associated with the induction of EMT and stemness markers
por: Lee, Kyung-Hwa, et al.
Publicado: (2014) -
Gene Therapy for Head and Neck Squamous Cell Carcinoma Using KITENIN (KAI1 COOH-Terminal Interacting Tetraspanin)-Antisense Therapy
por: Lee, Joon Kyoo, et al.
Publicado: (2011)