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MMP9 modulation improves specific neurobehavioral deficits in a mouse model of Alzheimer’s disease
BACKGROUND: Matrix metallopeptidase 9 (MMP9) has been implicated in a variety of neurological disorders, including Alzheimer’s disease (AD), where MMP9 levels are elevated in the brain and cerebrovasculature. Previously our group demonstrated apolipoprotein E4 (apoE4) was less efficient in regulatin...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152085/ https://www.ncbi.nlm.nih.gov/pubmed/34034683 http://dx.doi.org/10.1186/s12868-021-00643-2 |