Cargando…

MMP9 modulation improves specific neurobehavioral deficits in a mouse model of Alzheimer’s disease

BACKGROUND: Matrix metallopeptidase 9 (MMP9) has been implicated in a variety of neurological disorders, including Alzheimer’s disease (AD), where MMP9 levels are elevated in the brain and cerebrovasculature. Previously our group demonstrated apolipoprotein E4 (apoE4) was less efficient in regulatin...

Descripción completa

Detalles Bibliográficos
Autores principales: Ringland, Charis, Schweig, Jonas Elias, Eisenbaum, Maxwell, Paris, Daniel, Ait-Ghezala, Ghania, Mullan, Michael, Crawford, Fiona, Abdullah, Laila, Bachmeier, Corbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152085/
https://www.ncbi.nlm.nih.gov/pubmed/34034683
http://dx.doi.org/10.1186/s12868-021-00643-2