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CD38-directed CAR-T cell therapy: a novel immunotherapy strategy for relapsed acute myeloid leukemia after allogeneic hematopoietic stem cell transplantation

Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a potentially curative treatment for acute myeloid leukemia (AML). However, most patients experience relapse after allo-HSCT, with a poor prognosis, and treatment options are limited. The lack of an ideal targetable antigen is a major...

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Detalles Bibliográficos
Autores principales: Cui, Qingya, Qian, Chongsheng, Xu, Nan, Kang, Liqing, Dai, Haiping, Cui, Wei, Song, Baoquan, Yin, Jia, Li, Zheng, Zhu, Xiaming, Qu, Changju, Liu, Tianhui, Shen, Wenhong, Zhu, Mingqing, Yu, Lei, Wu, Depei, Tang, Xiaowen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152118/
https://www.ncbi.nlm.nih.gov/pubmed/34034795
http://dx.doi.org/10.1186/s13045-021-01092-4