Structural insights and inhibition mechanism of TMPRSS2 by experimentally known inhibitors Camostat mesylate, Nafamostat and Bromhexine hydrochloride to control SARS-coronavirus-2: A molecular modeling approach

Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) has been responsible for the cause of global pandemic Covid-19 and to date, there is no effective treatment available. The spike ‘S’ protein of SARS-CoV-2 and ACE2 of the host cell are being targeted to design new drugs to control Covid-19...

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Detalles Bibliográficos
Autores principales: Sonawane, Kailas D., Barale, Sagar S., Dhanavade, Maruti J., Waghmare, Shailesh R., Nadaf, Naiem H., Kamble, Subodh A., Mohammed, Ali Abdulmawjood, Makandar, Asiya M., Fandilolu, Prayagraj M., Dound, Ambika S., Naik, Nitin M., More, Vikramsinh B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152215/
https://www.ncbi.nlm.nih.gov/pubmed/34075338
http://dx.doi.org/10.1016/j.imu.2021.100597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152215/
https://www.ncbi.nlm.nih.gov/pubmed/34075338
http://dx.doi.org/10.1016/j.imu.2021.100597

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