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Structural insights and inhibition mechanism of TMPRSS2 by experimentally known inhibitors Camostat mesylate, Nafamostat and Bromhexine hydrochloride to control SARS-coronavirus-2: A molecular modeling approach
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) has been responsible for the cause of global pandemic Covid-19 and to date, there is no effective treatment available. The spike ‘S’ protein of SARS-CoV-2 and ACE2 of the host cell are being targeted to design new drugs to control Covid-19...
Autores principales: | Sonawane, Kailas D., Barale, Sagar S., Dhanavade, Maruti J., Waghmare, Shailesh R., Nadaf, Naiem H., Kamble, Subodh A., Mohammed, Ali Abdulmawjood, Makandar, Asiya M., Fandilolu, Prayagraj M., Dound, Ambika S., Naik, Nitin M., More, Vikramsinh B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier Ltd.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152215/ https://www.ncbi.nlm.nih.gov/pubmed/34075338 http://dx.doi.org/10.1016/j.imu.2021.100597 |
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