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Exosomal DLX6-AS1 from hepatocellular carcinoma cells induces M2 macrophage polarization to promote migration and invasion in hepatocellular carcinoma through microRNA-15a-5p/CXCL17 axis

BACKGROUND: Hepatocellular carcinoma (HCC) cells-secreted exosomes (exo) could stimulate M2 macrophage polarization and promote HCC progression, but the related mechanism of long non-coding RNA distal-less homeobox 6 antisense 1 (DLX6-AS1) with HCC-exo-mediated M2 macrophage polarization is largely...

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Detalles Bibliográficos
Autores principales: Wang, Lin-pei, Lin, Jing, Ma, Xiao-qiu, Xu, Dong-yao, Shi, Chun-feng, Wang, Wei, Jiang, Xiao-jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152341/
https://www.ncbi.nlm.nih.gov/pubmed/34039401
http://dx.doi.org/10.1186/s13046-021-01973-z