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High cytotoxicity of betulin towards fish and murine fibroblasts: Is betulin safe for nonneoplastic cells?

BACKGROUND: Betulin, a natural pentacyclic triterpene with the lupane structure that is present in significant amounts in the outer bark of birch, is known for its broad array of biological and pharmacological properties. Betulin has attracted attention as a potential, natural-origin antimicrobial s...

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Detalles Bibliográficos
Autores principales: Małaczewska, Joanna, Kaczorek-Łukowska, Edyta, Kazuń, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152350/
https://www.ncbi.nlm.nih.gov/pubmed/34034733
http://dx.doi.org/10.1186/s12917-021-02905-x