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CaMKII Phosphorylation Regulates Synaptic Enrichment of Shank3

SHANK3 is a large scaffolding protein in the postsynaptic density (PSD) that organizes protein networks, which are critical for synaptic structure and function. The strong genetic association of SHANK3 with autism spectrum disorder (ASD) emphasizes the importance of SHANK3 in neuronal development. S...

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Detalles Bibliográficos
Autores principales: Jeong, Jaehoon, Li, Yan, Roche, Katherine W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152369/
https://www.ncbi.nlm.nih.gov/pubmed/33568460
http://dx.doi.org/10.1523/ENEURO.0481-20.2021