New reductive rearrangement of N-arylindoles triggered by the Grubbs–Stoltz reagent Et(3)SiH/KO(t)Bu

N-Arylindoles are transformed into dihydroacridines in a new type of rearrangement, through heating with triethylsilane and potassium tert-butoxide. Studies indicate that the pathway involves (i) the formation of indole radical anions followed by fragmentation of the indole C2–N bond, and (ii) a rin...

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Detalles Bibliográficos
Autores principales: Smith, Andrew J., Dimitrova, Daniela, Arokianathar, Jude N., Kolodziejczak, Krystian, Young, Allan, Allison, Mark, Poole, Darren L., Leach, Stuart G., Parkinson, John A., Tuttle, Tell, Murphy, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152433/
https://www.ncbi.nlm.nih.gov/pubmed/34094060
http://dx.doi.org/10.1039/d0sc00361a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152433/
https://www.ncbi.nlm.nih.gov/pubmed/34094060
http://dx.doi.org/10.1039/d0sc00361a

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