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B Cell Activation and Escape of Tolerance Checkpoints: Recent Insights from Studying Autoreactive B Cells

Autoreactive B cells are key drivers of pathogenic processes in autoimmune diseases by the production of autoantibodies, secretion of cytokines, and presentation of autoantigens to T cells. However, the mechanisms that underlie the development of autoreactive B cells are not well understood. Here, w...

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Detalles Bibliográficos
Autores principales: Bonasia, Carlo G., Abdulahad, Wayel H., Rutgers, Abraham, Heeringa, Peter, Bos, Nicolaas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152463/
https://www.ncbi.nlm.nih.gov/pubmed/34068035
http://dx.doi.org/10.3390/cells10051190