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Principles and Practical Considerations for the Analysis of Disease-Associated Alternative Splicing Events Using the Gateway Cloning-Based Minigene Vectors pDESTsplice and pSpliceExpress

Splicing is an important RNA processing step. Genetic variations can alter the splicing process and thereby contribute to the development of various diseases. Alterations of the splicing pattern can be examined by gene expression analyses, by computational tools for predicting the effects of genetic...

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Detalles Bibliográficos
Autores principales: Putscher, Elena, Hecker, Michael, Fitzner, Brit, Lorenz, Peter, Zettl, Uwe Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152502/
https://www.ncbi.nlm.nih.gov/pubmed/34068052
http://dx.doi.org/10.3390/ijms22105154