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Enhanced SNP-sensing using DNA-templated reactions through confined hybridization of minimal substrates (CHOMS)
DNA or RNA templated reactions are attractive for nucleic acid sensing and imaging. As for any hybridization-based sensing, there is a tradeoff between sensitivity (detection threshold) and resolution (single nucleotide discrimination). Longer probes afford better sensitivity but compromise single n...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152519/ https://www.ncbi.nlm.nih.gov/pubmed/34122878 http://dx.doi.org/10.1039/d0sc00741b |