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Systematic quantification of the dynamics of newly synthesized proteins unveiling their degradation pathways in human cells
Proteins are continuously synthesized during cell growth and proliferation. At the same time, excessive and misfolded proteins have to be degraded, otherwise they are a burden to cells. Protein degradation is essential to maintain proteostasis in cells, and dysfunction of protein degradation systems...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152571/ https://www.ncbi.nlm.nih.gov/pubmed/34109028 http://dx.doi.org/10.1039/c9sc06479f |