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Systematic quantification of the dynamics of newly synthesized proteins unveiling their degradation pathways in human cells

Proteins are continuously synthesized during cell growth and proliferation. At the same time, excessive and misfolded proteins have to be degraded, otherwise they are a burden to cells. Protein degradation is essential to maintain proteostasis in cells, and dysfunction of protein degradation systems...

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Detalles Bibliográficos
Autores principales: Tong, Ming, Smeekens, Johanna M., Xiao, Haopeng, Wu, Ronghu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152571/
https://www.ncbi.nlm.nih.gov/pubmed/34109028
http://dx.doi.org/10.1039/c9sc06479f