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Peptidomimetics prepared by tail-to-side chain one component peptide stapling inhibit Alzheimer's amyloid-β fibrillogenesis

Alzheimer's disease (AD) is the most common form of dementia affecting the elderly population worldwide. Despite enormous efforts and considerable advancement in research, no therapeutic agents have come to light to date. However, many peptide-based and small molecule inhibitors interact effici...

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Detalles Bibliográficos
Autores principales: Kalita, Sujan, Kalita, Sourav, Paul, Ashim, Sarkar, Amar, Mandal, Bhubaneswar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152599/
https://www.ncbi.nlm.nih.gov/pubmed/34122880
http://dx.doi.org/10.1039/c9sc06076f