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Effects of sedimentation, microgravity, hydrodynamic mixing and air–water interface on α-synuclein amyloid formation
The formation of amyloid fibrils is a characterizing feature of a range of protein misfolding diseases, including Parkinson's disease. The propensity of native proteins to form such amyloid fibril, both in vitro and in vivo, is highly sensitive to the surrounding environment, which can alter th...
Autores principales: | Zhou, Jiangtao, Ruggeri, Francesco S., Zimmermann, Manuela R., Meisl, Georg, Longo, Giovanni, Sekatskii, Sergey K., Knowles, Tuomas P. J., Dietler, Giovanni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152616/ https://www.ncbi.nlm.nih.gov/pubmed/34094057 http://dx.doi.org/10.1039/d0sc00281j |
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