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MiR-15a-5p Confers Chemoresistance in Acute Myeloid Leukemia by Inhibiting Autophagy Induced by Daunorubicin

Anthracyclines remain a cornerstone of induction chemotherapy for acute myeloid leukemia (AML). Refractory or relapsed disease due to chemotherapy resistance is a major obstacle in AML management. MicroRNAs (miRNAs) have been observed to be involved in chemoresistance. We previously observed that mi...

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Detalles Bibliográficos
Autores principales: Bollaert, Emeline, Claus, Melissa, Vandewalle, Virginie, Lenglez, Sandrine, Essaghir, Ahmed, Demoulin, Jean-Baptiste, Havelange, Violaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152749/
https://www.ncbi.nlm.nih.gov/pubmed/34068078
http://dx.doi.org/10.3390/ijms22105153