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Metabolic Response of Triple-Negative Breast Cancer to Folate Restriction

Background: Triple-negative breast cancers (TNBCs), accounting for approximately 15% of breast cancers, lack targeted therapy. A hallmark of cancer is metabolic reprogramming, with one-carbon metabolism essential to many processes altered in tumor cells, including nucleotide biosynthesis and antioxi...

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Detalles Bibliográficos
Autores principales: Coleman, Michael F., O’Flanagan, Ciara H., Pfeil, Alexander J., Chen, Xuewen, Pearce, Jane B., Sumner, Susan, Krupenko, Sergey A., Hursting, Stephen D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152779/
https://www.ncbi.nlm.nih.gov/pubmed/34068120
http://dx.doi.org/10.3390/nu13051637