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Synthesis and evaluation of bis(imino)anthracene derivatives as G-quadruplex ligands

The synthesis of a small number of bis(imino)anthracene derivatives is reported. They were evaluated via NMR for binding efficacy to the G-quadruplex-forming oligonucleotide sequence (TTGGGTT) and show activity against the HeLa cancer cell line. These novel ligands are compared to previously synthes...

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Detalles Bibliográficos
Autores principales:	Coban, Tomris, Robertson, Cameron, Schwikkard, Sianne, Singer, Richard, LeGresley, Adam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	RSC 2021
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152782/ https://www.ncbi.nlm.nih.gov/pubmed/34124673 http://dx.doi.org/10.1039/d0md00428f

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