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Dynamic pH responsivity of triazole-based self-immolative linkers
Gating the release of chemical payloads in response to transient signals is an important feature of ‘smart’ delivery systems. Herein, we report a triazole-based self-immolative linker that can be reversibly paused or slowed and restarted throughout its elimination cascade in response to pH changes i...
Autores principales: | Roberts, Derrick A., Pilgrim, Ben S., Dell, Tristan N., Stevens, Molly M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152797/ https://www.ncbi.nlm.nih.gov/pubmed/34094059 http://dx.doi.org/10.1039/d0sc00532k |
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