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Applications of Circulating Tumor DNA in a Cohort of Phase I Solid Tumor Patients Treated With Immunotherapy

BACKGROUND: The correlation between blood-based tumor mutation burden (bTMB) and tissue-based tumor mutation burden(tTMB) has not been broadly tested in a multicancer cohort. Here, we assess the correlation between bTMB with tTMB in phase I trial patients treated with immunotherapy. As an explorator...

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Detalles Bibliográficos
Autores principales: Araujo, Daniel V, Wang, Ao, Torti, Dax, Leon, Alberto, Marsh, Kayla, McCarthy, Aoife, Berman, Hal, Spreafico, Anna, Hansen, Aaron R, Razak, Albiruni-Abdul, Bedard, Philippe L, Wang, Lisa, Plackmann, Eric, Chow, Helen, Bao, Hua, Wu, Xue, Pugh, Trevor J, Siu, Lillian L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152803/
https://www.ncbi.nlm.nih.gov/pubmed/34056539
http://dx.doi.org/10.1093/jncics/pkaa122