Activation of Nrf2/HO-1 by Peptide YD1 Attenuates Inflammatory Symptoms through Suppression of TLR4/MYyD88/NF-κB Signaling Cascade

In this study, we investigate the immunomodulatory effects of a novel antimicrobial peptide, YD1, isolated from Kimchi, in both in vitro and in vivo models. We establish that YD1 exerts its anti-inflammatory effects via up-regulation of the Nrf2 pathway, resulting in the production of HO-1, which su...

Descripción completa

Detalles Bibliográficos
Autores principales: Rahman, Md Saifur, Alam, Md Badrul, Kim, Young Kyun, Madina, Mst Hur, Fliss, Ismail, Lee, Sang Han, Yoo, Jin Cheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152960/
https://www.ncbi.nlm.nih.gov/pubmed/34068193
http://dx.doi.org/10.3390/ijms22105161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152960/
https://www.ncbi.nlm.nih.gov/pubmed/34068193
http://dx.doi.org/10.3390/ijms22105161

Ejemplares similares