Inhibiting quinolone biosynthesis of Burkholderia

2-Alkylquinolones are important signalling molecules of Burkholderia species. We developed a substrate-based chemical probe against the central quinolone biosynthesis enzyme HmqD and applied it in competitive profiling experiments to discover the first known HmqD inhibitors. The most potent inhibito...

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Detalles Bibliográficos
Autores principales: Prothiwa, Michaela, Filz, Verena, Oehler, Sebastian, Böttcher, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8153077/
https://www.ncbi.nlm.nih.gov/pubmed/34123319
http://dx.doi.org/10.1039/d0sc06167k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8153077/
https://www.ncbi.nlm.nih.gov/pubmed/34123319
http://dx.doi.org/10.1039/d0sc06167k

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