N-Alkylation of Anthracycline Antibiotics by Natural Sesquiterpene Lactones as a Way to Obtain Antitumor Agents with Reduced Side Effects

Anthracycline antitumor antibiotics are one of the promising classes of chemotherapeutic agents for cancer treatment. The main deterrent to their use is high toxicity to a healthy environment, including cumulative cardiotoxicity. In our work, bipharmacophore molecules containing in their structure a...

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Detalles Bibliográficos
Autores principales: Neganova, Margarita, Semakov, Alexey, Aleksandrova, Yulia, Yandulova, Ekaterina, Pukhov, Sergey, Anikina, Lada, Klochkov, Sergey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8153121/
https://www.ncbi.nlm.nih.gov/pubmed/34068225
http://dx.doi.org/10.3390/biomedicines9050547

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8153121/
https://www.ncbi.nlm.nih.gov/pubmed/34068225
http://dx.doi.org/10.3390/biomedicines9050547

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