Oxygen-Mediated Suppression of CD8+ T Cell Proliferation by Macrophages: Role of Pharmacological Inhibitors of HIF Degradation

Myeloid cell interactions with cells of the adaptive immune system are an essential aspect of immunity. A key aspect of that interrelationship is its modulation by the microenvironment. Oxygen is known to influence myelosuppression of T cell activation in part via the Hypoxia inducible (HIF) transcr...

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Detalles Bibliográficos
Autores principales: Gojkovic, Milos, Cunha, Pedro P., Darmasaputra, Gabriella S., Barbieri, Laura, Rundqvist, Helene, Veliça, Pedro, Johnson, Randall S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8153186/
https://www.ncbi.nlm.nih.gov/pubmed/34054802
http://dx.doi.org/10.3389/fimmu.2021.633586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8153186/
https://www.ncbi.nlm.nih.gov/pubmed/34054802
http://dx.doi.org/10.3389/fimmu.2021.633586

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