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Oxygen-Mediated Suppression of CD8+ T Cell Proliferation by Macrophages: Role of Pharmacological Inhibitors of HIF Degradation
Myeloid cell interactions with cells of the adaptive immune system are an essential aspect of immunity. A key aspect of that interrelationship is its modulation by the microenvironment. Oxygen is known to influence myelosuppression of T cell activation in part via the Hypoxia inducible (HIF) transcr...
Autores principales: | Gojkovic, Milos, Cunha, Pedro P., Darmasaputra, Gabriella S., Barbieri, Laura, Rundqvist, Helene, Veliça, Pedro, Johnson, Randall S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8153186/ https://www.ncbi.nlm.nih.gov/pubmed/34054802 http://dx.doi.org/10.3389/fimmu.2021.633586 |
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