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Targeting structural features of viral genomes with a nano-sized supramolecular drug
RNA targeting is an exciting frontier for drug design. Intriguing targets include functional RNA structures in structurally-conserved untranslated regions (UTRs) of many lethal viruses. However, computational docking screens, valuable in protein structure targeting, fail for inherently flexible RNA....
Autores principales: | Melidis, Lazaros, Styles, Iain B., Hannon, Michael J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8153246/ https://www.ncbi.nlm.nih.gov/pubmed/34123344 http://dx.doi.org/10.1039/d1sc00933h |
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