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Integrated genomic analysis reveals key features of long undecoded transcript isoform-based gene repression

Long undecoded transcript isoforms (LUTIs) represent a class of non-canonical mRNAs that downregulate gene expression through the combined act of transcriptional and translational repression. While single gene studies revealed important aspects of LUTI-based repression, how these features affect gen...

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Detalles Bibliográficos
Autores principales: Tresenrider, Amy, Morse, Kaitlin, Jorgensen, Victoria, Chia, Minghao, Liao, Hanna, van Werven, Folkert Jacobus, Ünal, Elçin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8153250/
https://www.ncbi.nlm.nih.gov/pubmed/33826921
http://dx.doi.org/10.1016/j.molcel.2021.03.013