Apigenin and Luteolin Regulate Autophagy by Targeting NRH-Quinone Oxidoreductase 2 in Liver Cells

Dietary flavonoids stimulate autophagy and prevent liver dysfunction, but the upstream signaling pathways triggered by these compounds are not well understood. Certain polyphenols bind directly to NRH-quinone oxidoreductase 2 (NQO2) and inhibit its activity. NQO2 is highly expressed in the liver, wh...

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Detalles Bibliográficos
Autores principales: Janda, Elzbieta, Martino, Concetta, Riillo, Concetta, Parafati, Maddalena, Lascala, Antonella, Mollace, Vincenzo, Boutin, Jean A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8153271/
https://www.ncbi.nlm.nih.gov/pubmed/34068281
http://dx.doi.org/10.3390/antiox10050776

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8153271/
https://www.ncbi.nlm.nih.gov/pubmed/34068281
http://dx.doi.org/10.3390/antiox10050776

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