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Production of a Foot-and-Mouth Disease Vaccine Antigen Using Suspension-Adapted BHK-21 Cells in a Bioreactor

The baby hamster kidney-21 (BHK-21) cell line is a continuous cell line used to propagate foot-and-mouth disease (FMD) virus for vaccine manufacturing. BHK-21 cells are anchorage-dependent, although suspension cultures would enable rapid growth in bioreactors, large-scale virus propagation, and cost...

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Detalles Bibliográficos
Autores principales: Park, Soonyong, Kim, Ji Yul, Ryu, Kyoung-Hwa, Kim, Ah-Young, Kim, Jaemun, Ko, Young-Joon, Lee, Eun Gyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8153295/
https://www.ncbi.nlm.nih.gov/pubmed/34068378
http://dx.doi.org/10.3390/vaccines9050505