Cargando…

Production of a Foot-and-Mouth Disease Vaccine Antigen Using Suspension-Adapted BHK-21 Cells in a Bioreactor

The baby hamster kidney-21 (BHK-21) cell line is a continuous cell line used to propagate foot-and-mouth disease (FMD) virus for vaccine manufacturing. BHK-21 cells are anchorage-dependent, although suspension cultures would enable rapid growth in bioreactors, large-scale virus propagation, and cost...

Descripción completa

Detalles Bibliográficos
Autores principales:	Park, Soonyong, Kim, Ji Yul, Ryu, Kyoung-Hwa, Kim, Ah-Young, Kim, Jaemun, Ko, Young-Joon, Lee, Eun Gyo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8153295/ https://www.ncbi.nlm.nih.gov/pubmed/34068378 http://dx.doi.org/10.3390/vaccines9050505

Ejemplares similares

Increasing Transfection Efficiency of Lipoplexes by Modulating Complexation Solution for Transient Gene Expression
por: Kim, Jaemun, et al.
Publicado: (2021)

Establishment of persistent infection with foot-and-mouth disease virus in BHK-21 cells
por: Huang, Xuan, et al.
Publicado: (2011)

Comparison of BHK-21 cell growth on microcarriers vs in suspension at 2L scale both in conventional bioreactor and single-use bioreactor (Univessel(® )SU)
por: Garcia, Lídia, et al.
Publicado: (2013)

Factors Involved in Removing the Non-Structural Protein of Foot-and-Mouth Disease Virus by Chloroform and Scale-Up Production of High-Purity Vaccine Antigens
por: Park, Sun Young, et al.
Publicado: (2022)

Quantitative Proteomic Analysis of BHK-21 Cells Infected with Foot-and-Mouth Disease Virus Serotype Asia 1
por: Guo, Hui-Chen, et al.
Publicado: (2015)

Validation of Pretreatment Methods for the In-Process Quantification of Foot-and-Mouth Disease Vaccine Antigens
por: Kim, Ah-Young, et al.
Publicado: (2021)

Development of a Potent Stabilizer for Long-Term Storage of Foot-and-Mouth Disease Vaccine Antigens
por: Kim, Ah-Young, et al.
Publicado: (2021)

On the entry of semliki forest virus into BHK-21 cells
por: Helenius, Ari, et al.
Publicado: (1980)

Comparison of High-Performance Liquid Chromatography with Sucrose Density Gradient Ultracentrifugation for the Quantification of Foot-and-Mouth Disease Vaccine Antigens
por: Kim, Ah-Young, et al.
Publicado: (2022)

Functions of cytoplasmic fibers in intracellular movements in BHK-21 cells
Publicado: (1978)

Determination of optimal age for single vaccination of growing pigs with foot-and-mouth disease bivalent vaccine in South Korea
por: KIM, Ah-Young, et al.
Publicado: (2017)

Efficient Removal of Non-Structural Protein Using Chloroform for Foot-and-Mouth Disease Vaccine Production
por: Park, Sun Young, et al.
Publicado: (2020)

Foot-and-Mouth Disease Virus Evades Innate Immune Response by 3C-Targeting of MDA5
por: Kim, Hyejin, et al.
Publicado: (2021)

Recombinant vesicular stomatitis virus glycoprotein carrying a foot-and-mouth disease virus epitope as a vaccine candidate
por: LEE, Hyang-Sim, et al.
Publicado: (2020)

Bufotenine is able to block rabies virus infection in BHK-21 cells
por: Vigerelli, Hugo, et al.
Publicado: (2014)

Caveolin-1 is involved in encephalomyocarditis virus replication in BHK-21 cells
por: Li, Qiongyi, et al.
Publicado: (2021)

Efficacy of Binary Ethylenimine in the Inactivation of Foot-and-Mouth Disease Virus for Vaccine Production in South Korea
por: Kim, Jae Young, et al.
Publicado: (2023)

Comparative study of bluetongue virus serotype 8 production on BHK-21 cells in a 50L Biostat(®) STR single-use bioreactors vs roller bottles
por: Garcia, Lídia, et al.
Publicado: (2013)

Reemergence of Foot-and-Mouth Disease, South Korea, 2000–2011
por: Park, Jong-Hyeon, et al.
Publicado: (2014)

THE EFFECTS OF CYTOCHALASIN B ON THE MICROFILAMENTS OF BABY HAMSTER KIDNEY (BHK-21) CELLS
por: Goldman, Robert D.
Publicado: (1972)

Insights into the Internalization and Retrograde Trafficking of Dengue 2 Virus in BHK-21 Cells
por: Shrivastava, Nidhi, et al.
Publicado: (2011)

Experimental infection of BHK21 and Vero cell lines with different Mycoplasma spp
por: Netto, Cristiane, et al.
Publicado: (2015)

Constant up-regulation of BiP/GRP78 expression prevents virus-induced apoptosis in BHK-21 cells with Japanese encephalitis virus persistent infection
por: Lyoo, Hey Rhyoung, et al.
Publicado: (2015)

Extended stability of cyclin D1 contributes to limited cell cycle arrest at G1-phase in BHK-21 cells with Japanese encephalitis virus persistent infection
por: Kim, Ji Young, et al.
Publicado: (2015)

Scale-Up Production of Type O and A Foot-and-Mouth Disease Bivalent Vaccine and Its Protective Efficacy in Pigs
por: Park, Sang-Hyun, et al.
Publicado: (2021)

Novel foot-and-mouth disease virus in Korea, July-August 2014
por: Park, Jong-Hyeon, et al.
Publicado: (2016)

Comparison of endocytosis pathways of Duck Tembusu virus in BHK-21 and duck embryo fibroblasts
por: Xian, Xuemei, et al.
Publicado: (2023)

Enhanced inhibition of foot-and-mouth disease virus by combinations of porcine interferon-α and antiviral agents
por: Kim, Su-Mi, et al.
Publicado: (2012)

Enteroviruses isolated from herpangina and hand-foot-and-mouth disease in Korean children
por: Park, KwiSung, et al.
Publicado: (2012)

Control of type O foot-and-mouth disease by vaccination in Korea, 2014–2015
por: Park, Jong-Hyeon, et al.
Publicado: (2018)

Rapid Engineering of Foot-and-Mouth Disease Vaccine and Challenge Viruses
por: Lee, Seo-Yong, et al.
Publicado: (2017)

Development of Monoclonal Antibody to Specifically Recognize VP0 but Not VP4 and VP2 of Foot-and-Mouth Disease Virus
por: Park, Sun Young, et al.
Publicado: (2022)

Production of Foot-and-Mouth Disease Type O and A Vaccine Antigens on a Pilot Scale and Determination of Optimal Amount of Antigen for Monovalent Vaccines
por: Kim, Jae Young, et al.
Publicado: (2023)

Application of Heparin Affinity Chromatography to Produce a Differential Vaccine without Eliciting Antibodies against the Nonstructural Proteins of the Serotype O Foot-and-Mouth Disease Viruses
por: Park, Sun Young, et al.
Publicado: (2020)

Synergistic effect of ribavirin and vaccine for protection during early infection stage of foot-and-mouth disease
por: Choi, Joo-Hyung, et al.
Publicado: (2018)

Proceedings: Mechanism of action studies with IRCF 159: effects on the growth and morphology of BHK-21S cells.
por: Stephens, T. C., et al.
Publicado: (1974)

THE ROLE OF THREE CYTOPLASMIC FIBERS IN BHK-21 CELL MOTILITY : I. Microtubules and the Effects of Colchicine
por: Goldman, Robert D.
Publicado: (1971)

Ultrastructure of microfilament bundles in baby hamster kidney (BHK-21) cells. The use of tannic acid
Publicado: (1979)

Expression of Factor X in BHK-21 Cells Promotes Low Pathogenic Influenza Viruses Replication
por: Shahsavandi, Shahla, et al.
Publicado: (2015)

Heparin sulfate is the attachment factor of duck Tembus virus on both BHK21 and DEF cells
por: Wu, Shaoxiong, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_heckmgo081mbem0d0um4hldv32