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Dual R108K and G189D Mutations in the NS1 Protein of A/H1N1 Influenza Virus Counteract Host Innate Immune Responses

Influenza A viruses (IAV) modulate host antiviral responses to promote growth and pathogenicity. Here, we examined the multifunctional IAV nonstructural protein 1 (NS1) of influenza A virus to better understand factors that contribute to viral replication efficiency or pathogenicity. In 2009, a pand...

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Detalles Bibliográficos
Autores principales: Huang, Meng-Ting, Zhang, Sen, Wu, Ya-Nan, Li, Wei, Li, Yu-Chang, Zhou, Chang-Shuai, Kang, Xiao-Ping, Jiang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8153306/
https://www.ncbi.nlm.nih.gov/pubmed/34068322
http://dx.doi.org/10.3390/v13050905