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Structural Studies Providing Insights into Production and Conformational Behavior of Amyloid-β Peptide Associated with Alzheimer’s Disease Development

Alzheimer’s disease is the most common type of neurodegenerative disease in the world. Genetic evidence strongly suggests that aberrant generation, aggregation, and/or clearance of neurotoxic amyloid-β peptides (Aβ) triggers the disease. Aβ accumulates at the points of contact of neurons in ordered...

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Detalles Bibliográficos
Autores principales: Urban, Anatoly S., Pavlov, Konstantin V., Kamynina, Anna V., Okhrimenko, Ivan S., Arseniev, Alexander S., Bocharov, Eduard V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8153327/
https://www.ncbi.nlm.nih.gov/pubmed/34068293
http://dx.doi.org/10.3390/molecules26102897