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Increased elastase sensitivity and decreased intramolecular interactions in the more transmissible 501Y.V1 and 501Y.V2 SARS-CoV-2 variants’ spike protein–an in silico analysis

Two SARS-CoV-2 variants of concern showing increased transmissibility relative to the Wuhan virus have recently been identified. Although neither variant appears to cause more severe illness nor increased risk of death, the faster spread of the virus is a major threat. Using computational tools, we...

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Detalles Bibliográficos
Autores principales: Pokhrel, Suman, Kraemer, Benjamin R., Lee, Lucia, Samardzic, Kate, Mochly-Rosen, Daria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8153447/
https://www.ncbi.nlm.nih.gov/pubmed/34038453
http://dx.doi.org/10.1371/journal.pone.0251426