STING regulates metabolic reprogramming in macrophages via HIF-1α during Brucella infection

Macrophages metabolic reprogramming in response to microbial insults is a major determinant of pathogen growth or containment. Here, we reveal a distinct mechanism by which stimulator of interferon genes (STING), a cytosolic sensor that regulates innate immune responses, contributes to an inflammato...

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Detalles Bibliográficos
Autores principales: Gomes, Marco Tulio R., Guimarães, Erika S., Marinho, Fabio V., Macedo, Isabella, Aguiar, Eric R. G. R., Barber, Glen N., Moraes-Vieira, Pedro M. M., Alves-Filho, José Carlos, Oliveira, Sergio C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8153530/
https://www.ncbi.nlm.nih.gov/pubmed/33989349
http://dx.doi.org/10.1371/journal.ppat.1009597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8153530/
https://www.ncbi.nlm.nih.gov/pubmed/33989349
http://dx.doi.org/10.1371/journal.ppat.1009597

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