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STING regulates metabolic reprogramming in macrophages via HIF-1α during Brucella infection
Macrophages metabolic reprogramming in response to microbial insults is a major determinant of pathogen growth or containment. Here, we reveal a distinct mechanism by which stimulator of interferon genes (STING), a cytosolic sensor that regulates innate immune responses, contributes to an inflammato...
Autores principales: | Gomes, Marco Tulio R., Guimarães, Erika S., Marinho, Fabio V., Macedo, Isabella, Aguiar, Eric R. G. R., Barber, Glen N., Moraes-Vieira, Pedro M. M., Alves-Filho, José Carlos, Oliveira, Sergio C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8153530/ https://www.ncbi.nlm.nih.gov/pubmed/33989349 http://dx.doi.org/10.1371/journal.ppat.1009597 |
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