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β-Cyclodextrin-poly (β-Amino Ester) Nanoparticles Are a Generalizable Strategy for High Loading and Sustained Release of HDAC Inhibitors

[Image: see text] Therapeutic development of histone deacetylase inhibitors (HDACi) has been hampered by a number of barriers to drug delivery, including poor solubility and inadequate tissue penetration. Nanoparticle encapsulation could be one approach to improve the delivery of HDACi to target tis...

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Detalles Bibliográficos
Autores principales: Chaudhuri, Sauradip, Fowler, Martha J., Baker, Cassandra, Stopka, Sylwia A., Regan, Michael S., Sablatura, Lindsey, Broughton, Colton W., Knight, Brandon E., Stabenfeldt, Sarah E., Agar, Nathalie Y. R., Sirianni, Rachael W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8153536/
https://www.ncbi.nlm.nih.gov/pubmed/33905245
http://dx.doi.org/10.1021/acsami.0c22587