A Safety and Tolerability Study of Thin Film Freeze-Dried Tacrolimus for Local Pulmonary Drug Delivery in Human Subjects

Due to the low and erratic bioavailability of oral tacrolimus (TAC), the long-term survival rate following lung transplantation remained low compared to other solid organs. TAC was reformulated and developed as inhaled formulations by thin film freezing (TFF). Previous studies reported that inhaled...

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Detalles Bibliográficos
Autores principales: Sahakijpijarn, Sawittree, Beg, Moeezullah, Levine, Stephanie M., Peters, Jay I., Williams, Robert O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8153550/
https://www.ncbi.nlm.nih.gov/pubmed/34068391
http://dx.doi.org/10.3390/pharmaceutics13050717

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8153550/
https://www.ncbi.nlm.nih.gov/pubmed/34068391
http://dx.doi.org/10.3390/pharmaceutics13050717

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