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Simple Fluorogenic Cellular Assay for Histone Deacetylase Inhibitors Based on Split-Yellow Fluorescent Protein and Intrabodies

[Image: see text] Histone deacetylase (HDAC) inhibitors that regulate the posttranslational modifications of histone tails are therapeutic drugs for many diseases such as cancers, neurodegenerative diseases, and asthma; however, convenient and sensitive methods to measure the effect of HDAC inhibito...

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Detalles Bibliográficos
Autores principales: Ohmuro-Matsuyama, Yuki, Kitaguchi, Tetsuya, Kimura, Hiroshi, Ueda, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8153662/
https://www.ncbi.nlm.nih.gov/pubmed/34056159
http://dx.doi.org/10.1021/acsomega.0c06281