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Simple Fluorogenic Cellular Assay for Histone Deacetylase Inhibitors Based on Split-Yellow Fluorescent Protein and Intrabodies
[Image: see text] Histone deacetylase (HDAC) inhibitors that regulate the posttranslational modifications of histone tails are therapeutic drugs for many diseases such as cancers, neurodegenerative diseases, and asthma; however, convenient and sensitive methods to measure the effect of HDAC inhibito...
Autores principales: | Ohmuro-Matsuyama, Yuki, Kitaguchi, Tetsuya, Kimura, Hiroshi, Ueda, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8153662/ https://www.ncbi.nlm.nih.gov/pubmed/34056159 http://dx.doi.org/10.1021/acsomega.0c06281 |
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